2020年1月3日,我们将进行2020年度第1次Journal Club,组织者为陈洁,参与人有金思慧,刑丽敏。Journal club的总结以及报告内容(Slides)会在会后张贴出来。
报告主题:Sex and the Single Fly: A Perspective on the Career of Bruce S. Baker
报告内容:
9:00-9:30 happy hour
9:30-10:00 陈洁 Sex Determination and Dosage Compensation in Drosophila
10:00-10:30 金思慧 The Development of Sexually Dimorphic Structures and the Evolution of Sex
10:30-11:00 刑丽敏 Sex Behavior Meets the Sex Determination Regulatory Hierarchy: The Genetic Control of Sexual Behavior
11:00- 讨论
Bruce had an exceptionally rich academic career. He made major, revelatory contributions to scientific knowledge, with the publication of >100 academic papers from his laboratory. While he and his trainees examined several research topics using different approaches, he spent 4 decades deeply focused on elaborating upon the theme of his first major sex determination paper “Sex and the single cell. I. On the action of major loci affecting sex determination in Drosophila melanogaster” (Baker and Ridge 1980). This theme took the laboratory on a journey through a range of intellectual topics, from reproductive behavior, to alternative pre-mRNA splicing, to sex chromosome evolution, sex differences in developmental biology, and many more. Each topic was approached with a high level of scientific rigor, curiosity, and ingenuity, through Bruce’s mentoring and training the next generation of scientists. Bruce told members of his laboratory that he had planned for a series of “Sex and the single cell” papers. However, time passed, and the second one arrived a full 30 years after the first, titled “Sex and the single cell. II. There is a time and place for sex” (Robinett et al. 2010). It is unfortunate for the scientific community that we will not know the next chapters, as they would have been written by Bruce. (Andrew et al., Sex and the Single Fly: A Perspective on the Career of Bruce S. Baker, 2019, Genetics, 212: 365–376)